Full title: Prognostication of Oxygen Requirement in non-severe SARS-CoV-2 respiratory infection (PRIORITY)
Funder: OUCRU (Wellcome funding)
Principal Investigator: Sakib Burza (MSF Spain)
OUCRU Co-Investigator: Sophie Yacoub
In adults presenting to care with non-severe COVID-19, can subsequent need for oxygen be predicted from parameters measured at the time of arrival at a healthcare facility?
- To identify clinical and biochemical prognostic markers in adults with non-severe COVID-19, with a focus on:
- Aiding safe discharge from a healthcare facility (i.e. a high NPV);
- Near-term impact on COVID-19 interventions in a resource-limited setting (i.e. simple demographic variables and biochemical markers for which near-patient / POCTs are commercially available or in late-stage development).
- To determine the ability of an LMIC-friendly point-of-care or near-patient prognostic test to predict subsequent oxygen requirement in adults with non-severe COVID-19.
- To demonstrate that operational research can be conducted ethically and effectively in the context of a pandemic in a resource-limited setting without detracting from the emergency response.