Prof Cameron Simmons

Name

Professor Cameron Simmons

Position

Senior Research Fellow and Professor, University of Melbourne and University of Oxford.

About

Cam Simmons is an infectious disease scientist and internationally recognized for his work in dengue. Cam and his colleagues have led the field in trialing therapeutic interventions for dengue and are prominent in deciphering its pathogenesis and epidemiology. Cam is a principal investigator in the Eliminate Dengue Project which uses Wolbachia as a novel entomological approach to reduce the incidence of dengue.

Research Group

Dengue

Publications

Professor Simmons has published more than 100 articles in international journals.

5 key publications/journal articles:

Nguyet MN, Duong TH, Trung VT, Nguyen TH, Tran CN, Long VT, Dui le T, Nguyen HL, Farrar JJ, Holmes EC, Rabaa MA, Bryant JE, Nguyen TT, Nguyen HT, Nguyen LT, Pham MP, Nguyen HT, Luong TT, Wills B, Nguyen CV, Wolbers M, Simmons CP. Host and viral features of human dengue cases shape the population of infected and infectious Aedes aegypti mosquitoes. Proc Natl Acad Sci U S A. 2013 May 28;110(22):9072-7. PMID: 23674683

Nguyen NM, Tran CN, Phung LK, Duong KT, Huynh Hle A, Farrar J, Nguyen QT, Tran HT, Nguyen CV, Merson L, Hoang LT, Hibberd ML, Aw PP, Wilm A, Nagarajan N, Nguyen DT, Pham MP, Nguyen TT, Javanbakht H, Klumpp K, Hammond J, Petric R, Wolbers M, Nguyen CT, Simmons CP. A randomized, double-blind placebo controlled trial of balapiravir, a polymerase inhibitor, in adult dengue patients. J Infect Dis 2012: Jul 17. J Infect Dis. 2013 May 1;207(9):1442-50. PMID: 22807519

Khor CC, Chau TN, Pang J, Davila S, Long HT, Ong RT, Dunstan SJ, Wills B, Farrar J, Van Tram T, Gan TT, Binh NT, Tri le T, Lien le B, Tuan NM, Tham NT, Lanh MN, Nguyet NM, Hieu NT, Van N Vinh Chau N, Thuy TT, Tan DE, Sakuntabhai A, Teo YY, Hibberd ML, Simmons CP. Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. Nature Genetics 2011; 43(11): 1139-41. PMID: 22001756

Neil M. Ferguson, Duong Thi Hue Kien, Hannah Clapham, Ricardo Aguas, Vu Tuan Trung, Tran Nguyen Bich Chau, Jean Popovici, Peter A. Ryan, Scott L. O’Neill, Elizabeth A. McGraw, Vo Thi Long, Le Thi Dui, Hoa L. Nguyen, Nguyen Van Vinh Chau, Bridget Wills, Cameron P. Simmons. Modeling the impact on virus transmission of Wolbachia-mediated blocking of dengue virus infection of Aedes aegypti. Sci. Transl. Med. 7, 279ra37 (2015). PMID: 25787763

Katherine L. Anders, Le Hong Nga, Nguyen Thi Van Thuy, Tran Van Ngoc, Cao Thi Tam, Luong Thi Hue Tai, Nguyen Thanh Truong, Huynh Thi Le Duyen, Vu Tuan Trung, Duong Thi Hue Kien, Marcel Wolbers, Bridget Wills, Nguyen Van Vinh Chau, Nguyen Dac Tho, Cameron P. Simmons. Households as Foci for Dengue Transmission in Highly Urban Vietnam. PLoS Negl Trop Dis. 2015 February; 9(2): e0003528. PMID: 25680106

 

5 key publications – books/monographs etc.

Simmons CP, Farrar, J, NVV Chau, B. Wills. Current Concepts: Dengue. N Engl J Med 2012; 366(15): 1423-32.

Whitehorn J, Hubbard S, Anders K, Quyen NTH, Simmons CP. Dengue Pathogenesis- Host Factors. In: Gubler, editor. Dengue and Dengue Hemorrhagic Fever. 2nd ed.

Whitehorn J, Simmons CP. The pathogenesis of dengue. In: Vaccine. 2011 Sep 23;29(42):7221-8.

Simmons CP, Wolbers M, Nguyen MN, Whitehorn J, Shi PY, Young P, et al. Therapeutics for dengue: recommendations for design and conduct of early-phase clinical trials. PLoS Negl Trop Dis. 2012;6(9):e1752.

Professor Simmons’ Google Scholar Profile.