Pham Van Toi

Name

Pham Van Toi, MSc Pharmacy

Position

Pharmacist, Head of Clinical Pharmacology Laboratory.

About

Pham Van Toi has more than 10 years of experience in bioanalytical method development and validation. He is currently responsible for the Clinical Pharmacology lab; which is based within OUCRU in partnership with Hospital for Tropical Diseases Ho Chi Minh City, Viet Nam. Pham Van Toi joined OUCRU in 2004 as senior research pharmacist. From 2006 to 2007, he was member of Pharmacy Committee of SEA Influenza Clinical Research Network (SEAICRN) and supported setting up the Pharmacy Department in HTD, CH1 and CH2 in HCMC for SEAICRN. Besides, he was involved in designing and performing the pharmacokinetic study: Orally formulated artemisinin in healthy fasting Vietnamese male subjects: a randomized, four-sequence, open-label, pharmacokinetic crossover study. He then has been assigned as pharmacologist and worked for the new Pharmacology Lab, which was established in 2008 within OUCRU. His main research areas are designed to adapt and satisfy to the demands of the research groups and clinical personnel responsible for patient cares including to develop, validate the HPLC methods to measure concentrations of many drugs (Acyclovir, Antituberculosis, Levofloxacin, Beta-lactam antibiotics, Chloroquine) in biological fluids such as plasma, blood, urine and Cerebro-Spinal Fluid (CSF) for pharmacokinetic studies.

Prior to OUCRU, Pham Van Toi worked as lecturer for Department of Botany in Faculty of Pharmacy-University of Medicine and Pharmacy Ho Chi Minh City (1983-1990), then he moved to Roussel Viet Nam (Vietnamese-French Joint-venture Pharmaceutical Company) and undertook different positions: Product manager, Marketing Director Associate, Zone Manager, Logistic and Purchasing Manager (1990-2004). Pham Van Toi, graduated as Pharmacist in 1982, and obtained his Master of Science in Pharmacy with thesis “Pharmacokinetics of Ofloxacin in Vietnamese healthy Volunteers” in 2001 from University of Medicine and Pharmacy in Ho Chi Minh City, Viet Nam. He is author and co-author in publishing about 7 articles in journals.

Publications

Nguyen-Pouplin J, Pouplin T, Van TP, The TD, Thi DN, Farrar J, et al. Dextran Fractional Clearance Studies in Acute Dengue Infection. PLoS Negl Trop Dis. 2011 Aug;5(8):e1282. doi: 10.1371/journal.pntd.0001282. Epub 2011 Aug 23. PMID: 21886850

Pouplin T, Pouplin JN, Van Toi P, Lindegardh N, Rogier van Doorn H, Hien TT, et al. Valacyclovir for Herpes Simplex Encephalitis. Antimicrob Agents Chemother. 2011 Jul;55(7):3624-6. doi: 10.1128/AAC.01023-10. Epub 2011 May 16. PMID: 21576427

Hien TT, Hanpithakpong W, Truong NT, Dung NT, Toi PV, Farrar J, et al. Orally formulated artemisinin in healthy fasting Vietnamese male subjects: a randomized, four-sequence, open-label, pharmacokinetic crossover study. Clin Ther. 2011 May;33(5):644-54. doi: 10.1016/j.clinthera.2011.04.017. PMID: 21665048

Lindegardh N, Tarning J, Toi PV, Hien TT, Farrar J, Singhasivanon P, et al. Quantification of artemisinin in human plasma using liquid chromatography coupled to tandem mass spectrometry. J Pharm Biomed Anal. 2009 Apr 5;49(3):768-73. doi: 10.1016/j.jpba.2008.12.014. Epub 2008 Dec 24. PMID: 19162422

Pham Van Toi, Dang Van Hoa, Mai Phuong Mai, Vo Thi Bach Hue, Dong Thi Hoai Tam, Tran Tinh Hien and Christopher Parry. Pharmacokinetic of ofloxacin tablets in Vietnamese Healthy Volunteers. Duoc Hoc Magazine. Oct 2002;318:13-17. Vietnamese.