Prof. H Rogier van Doorn

Name

Prof H Rogier van Doorn, MD PhD.

MD – Consultant Clinical Microbiology and Virology, Amsterdam University Medical Centers location Academic Medical Center, Amsterdam (NL), Faculty of Medicine, 1990-1998 2003-2007.

Registrations: RIBIZ (NL) 69052473801, GMC (UK) 6168758.

PhD – University of Amsterdam (NL), Faculty of Medicine, Amsterdam University Medical Centers location Academic Medical Center, Department of Medical Microbiology, 1999-2005.

MSc – Medical Biology, University of Amsterdam (NL), Faculty of Biology, 1994-1996

 

Position

Director of OUCRU Hanoi

 

About

Rogier is a Clinical Microbiologist from the Netherlands who has worked at OUCRU Ho Chi Minh City from 2007-2015 and now leads the OUCRU Hanoi unit, hosted by the National Hospital of Tropical Diseases.

As head of the virology lab for the Southeast Asian Infectious Disease Clinical Research Network he has led analysis of several diagnostic and intervention studies on human influenza, developed diagnostic lab capacity in local hospitals and a BSL3/SAPO4 facility at OUCRU. He has worked on diagnostics, preparedness and clinical research of emerging infections, and set up and led a multidisciplinary research programme on Hand, Foot, and Mouth Disease.

In Hanoi, based at the National Hospital for Tropical Diseases, Rogier leads a research programme on antimicrobial resistance covering the spectrum from laboratory detection of resistance mechanisms, pathogen whole genome sequencing, implementation research, public and policy engagement.

OUCRU Hanoi has established a network of 16 hospitals for surveillance of antimicrobial consumption and resistance. This network was supported further as part of the Fleming Fund pilot and has been adopted by the Ministry of Health as the National AMR surveillance network. A reference laboratory for AMR was established at the National Hospital for Tropical Diseases in the same pilot. Rogier is leading a number of implementation studies of quality standards, AMR surveillance improvement and antimicrobial stewardship.

Together with the National Insititute of Hygiene and Epidemiology, OUCRU Hanoi conducts studies on influenza epidemiology and antimicrobial resistance in the longest active unvaccinated influenza cohort in a semirural community south of Hanoi.

 

Publications

On 23 May 2019 Rogier has published 126 original research papers in PubMED indexed journals, more than 100 affiliated with OUCRU.

 

Key PubMED indexed publications:

T. T. Nga, Ngan T. T. D., Ninh T. T. H., Hung T. M., Bich V. T. N., Long H. B., van Doorn H. R., Dung V. T. V., Cals J. W. L., Chandna A., Lubell Y., Nadjm B., Thwaites G. E., Wolbers M., Kinh N. V. and Wertheim H. F. L. Point-of-care C-reactive protein testing to reduce inappropriate use of antibiotics for non-severe acute respiratory infections in adults and children in the Vietnamese primary health care setting: a multi-centre randomised controlled trial. (NCT01918579) Lancet Glob Health. 2016. 4(9):e633–641. PMID: 27495137.

Nadjm, Dat V. Q., Campbell J. I., Dung V. T. V., Torre A., Tu N. T. C., Van N. T. T., Trinh D. T., Lan N. P. H., Trung N. V., Hang N. T. T., Hoi L. T., Baker S., Wolbers M., Chau N. V. V., Kinh N. V., Thwaites G. E., van Doorn H. R. and Wertheim H. F. A randomised controlled trial of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDITOF-MS) versus conventional microbiological methods for identifying pathogens: impact on optimal antimicrobial therapy of invasive bacterial and fungal infections in Vietnam. J Infect. PMID: 30914268.

South East Asia Infectious Disease Clinical Research Network. Causes and Outcomes of Sepsis in Southeast Asia: A Multinational Multicentre Cross-sectional Study. Lancet Global Health. 2016. 5(2):e157-167. PMID: 28104185.

South East Asia Infectious Disease Clinical Research Network. Effect of double dose oseltamivir on clinical and virological outcomes in children and adults admitted to hospital with severe influenza: double blind randomised controlled trial. Br Med J. 2013; 346:f3039. PMID: 23723457

M. T. Van, Anh N. T., Thanh T. T., Hang V. T. T., Nhu L. N. T., Ny N. T. H., Nhat L. T. H., Hong N. T. T., Hung N. T., Nhan L. N. T., Khanh T. H., Quy D. T., Tuan H. M., Viet H. L., Viet D. C., Nam N. T., Thanh N. T. M., Sabanathan S., Qui P. T., Chau N. V. V., Thwaites G. E., Wills B., Thwaites C. L., Tan L. V. and van Doorn H. R. Clinical and aetiological study of hand, foot and mouth disease in southern Vietnam, 2013-2015: inpatients and outpatients. Int J Infect Dis. 2019. 80:1-9. PMID: 30550944.

Khanh TH, Sabanathan S, Thanh TT, Thoa le PK, Thuong TC, Hang Vt, Farrar J, Hien TT, Chau Nv, van Doorn HR. Enterovirus 71 associated Hand, Foot and Mouth Disease, southern Vietnam, 2011. CME activity. Emerg Infect Dis. 2012; 18(12):2002-5. PMID: 23194699

Hien TT, Boni MF, Bryant JE, Ngan TT, Wolbers M, Nguyen TD, Truong NT, Dung NT, Ha do Q, Hien VM, Thanh TT, Nhu le NT, Uyen le TT, Nhien PT, Chinh NT, Chau NV, Farrar J, van Doorn HR. Early pandemic influenza (2009H1N1) in Ho Chi Minh City, Vietnam: a clinical virological and epidemiological analysis. PLoS Med. 2010; 7(5):e1000277. PMID: 20502525

 

Key publications – books/monographs etc:

V. Kinh, Wertheim H. F. L., Thwaites G. E., Khue L. N., Thai C. H., Khoa N. T., Ha N. T. B., Trung N. V., Crook D., van Doorn H. R. Developing an antimicrobial resistance reference laboratory and surveillance programme in Viet Nam: A Fleming Fund pilot project. Lancet Global Health. 2017. 5(12):e1186. PMID: 29132611.

Li R, van Doorn HR, Wertheim HF, Khue LN, Ha NT, Dat VQ, Hanh CT, Nga DT, Trang NN, Nadjm B, Cluzeau F, Kinh NV, Trung NV, Huong NT, Chau NQ, Huong Q, Thao LT, Hong LT, Oanh TT, Islam J, Roberts CM, Chalkidou K. Combating Antimicrobial Resistance: Quality Standards for Prescribing for Respiratory Infections in Vietnam. Lancet Global Health. 2016. 4(11):e789. PMID: 27765287.

Viral respiratory infections. In: Hunter’s Tropical Medicine and Emerging infectious Diseases. 9th and 10th ed. Oxford: Elsevier; 2019. ISBN: 978-1-4160-4390-4 and 978-0-323-55512-8.

Respiratory viruses and atypical bacteria. In: Manson’s Tropical Diseases. 23rd ed. London: W. B. Saunders Ltd; 2013. ISBN: 978-0-7020-5101-2

Enteroviruses (including Rhinoviruses) and Parechoviruses. In: Manual of Childhood Infections – The Blue Book. 4th edition, Oxford University Press, Oxford (UK). 2015. ISBN: 978-0-19-872922-8

Van Doorn HR. Emerging Infectious Diseases. Medicine. 2013 and 2017. Review. PMID: 24563608

Prof Van Doorn’s PubMed indexed publications on NCBI

www.ncbi.nlm.nih.gov/myncbi/browse/collection/40069246