{"id":7913,"date":"2022-07-21T13:41:58","date_gmt":"2022-07-21T06:41:58","guid":{"rendered":"https:\/\/www.oucru.org\/?p=7913"},"modified":"2023-10-09T15:40:21","modified_gmt":"2023-10-09T08:40:21","slug":"world-hepatitis-day","status":"publish","type":"post","link":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/","title":{"rendered":"World Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C"},"content":{"rendered":"

July 28 is World Hepatitis Day.<\/p>\n

According to the World Health Organisation, 10 \u2013 15 per cent of Vietnam\u2019s population is estimated to have viral hepatitis, including 1,07 million people who have Hepatitis C. Over 90 per cent of those who have Hepatitis C are not aware of their positive status.<\/p>\n

OUCRU, the Hospital for Tropical Diseases (Ho Chi Minh City), and Vietnam\u2019s National Hospital for Tropical Diseases (Hanoi) have been collaborating on Hepatitis C clinical trials since 2018. Our research is centred around predictive factors for selecting persons who could be successfully treated with shorter durations of antiviral therapy for Hepatitis C.<\/p>\n

Currently, directly acting antiviral (DAA) therapy for Hepatitis C (HCV) offers high cure rates to those able to adhere to standard durations of treatment. In low- and middle-income countries like Vietnam, where treatment is limited to second-generation NS5A\/NS5B-inhibitor combinations, the standard treatment is at least 12 weeks. This duration presents a barrier to successful engagement in care for some populations, hampering the elimination of HCV as a public health threat. Novel treatment strategies are required for hard-to-reach individuals, such as people who inject drugs and those with no fixed abode.<\/p>\n

In addition, in Vietnam, DAA therapy for Hepatitis C remains prohibitively expensive for many of those infected. A standard twelve-week course of sofosbuvir and daclatasvir (SOF\/DCV) was priced at US$2,417 \u2013 $2,472 in Ho Chi Minh City in 2019. Despite the government subsidising 50% of drug costs since, the Ministry of Health estimates only 1,000 individuals accessed DAA treatment through health insurance in 2019 and 2,700 in 2020.<\/p>\n

The World Health Organisation has called for research into predictive factors for selecting persons who could be successfully treated with shorter durations of therapy, which could expand access to treatment and reduce drug costs.<\/p>\n

We completed a small pilot study in 2020<\/a>, looking at the early virological response as a means of guiding the duration of therapy of SOF\/DCV, which remains the lowest-priced and most widely available treatment option globally.<\/p>\n

We are also running an ongoing larger multi-arm randomised controlled trial exploring three different treatment shortening strategies for Hep C with two different drug combinations. We expect to complete recruitment in early 2023.<\/p>\n

In addition, our team of OUCRU researchers recently performed a systematic review and meta-analysis of the seroprevalence of Hepatitis B, C and D in Vietnam<\/a> from 1990-2020, which was published in The Lancet Western Pacific in May 2022. We found that while blood safety has improved, a renewed focus on HBV vaccination at birth and targeted HCV screening and treatment of people who inject drugs are urgently required to meet elimination targets.<\/p>\n

To date, these clinical trials have recruited from populations already engaged in care at the HTD. Participants are aware of HCV infection and its implications and are well-motivated to seek treatment. Since our clinical trials are investigating the efficacy of treatment strategies that could be used to treat underserved populations (e.g. ultrashort or intermittent therapy), should these strategies have efficacy as hoped, it is crucial to develop innovative ways to engage with these \u2018hard-to-reach\u2019 populations, such as people who inject drugs (PWID), men who have sex with men, commercial sex workers, as well as low-income communities.<\/p>\n

OUCRU\u2019s social science and public engagement teams are currently working with these underrepresented groups, using community-based participatory research (CBPR) to engage with communities to create community-led strategies to improve linkages to care and treatment for populations at risk for viral hepatitis.<\/p>\n

\"\"<\/a>
CBPR groups practising Venn Diagram as part of CBPR activities to identify stakeholders having impacts on underserved communities at risk of Hep C.<\/em><\/figcaption><\/figure>\n

These studies are currently ongoing, with a positive impact on the participants. We hope to have a more significant impact on the treatment strategy and access to care for patients with Hepatitis C in Vietnam and worldwide in the future.<\/p>\n","protected":false},"excerpt":{"rendered":"

July 28 is World Hepatitis Day. According to the World Health Organisation, 10 \u2013 15 per cent of Vietnam\u2019s population is estimated to have viral hepatitis, including 1,07 million people […]<\/p>\n","protected":false},"author":28,"featured_media":7915,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":"","_wp_rev_ctl_limit":""},"categories":[79],"tags":[33],"class_list":["post-7913","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-news"],"acf":[],"yoast_head":"\nWorld Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C - OUCRU<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/\" \/>\n<meta property=\"og:locale\" content=\"id_ID\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"World Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C - OUCRU\" \/>\n<meta property=\"og:description\" content=\"July 28 is World Hepatitis Day. According to the World Health Organisation, 10 \u2013 15 per cent of Vietnam\u2019s population is estimated to have viral hepatitis, including 1,07 million people […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/\" \/>\n<meta property=\"og:site_name\" content=\"OUCRU\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/OUCRUVN\/\" \/>\n<meta property=\"article:published_time\" content=\"2022-07-21T06:41:58+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-10-09T08:40:21+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.oucru.org\/wp-content\/uploads\/2022\/07\/Stakeholder-meeting-with-NGOs-October-2021.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"4032\" \/>\n\t<meta property=\"og:image:height\" content=\"2268\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Chi Ngo Huyen\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@OUCRU_Programme\" \/>\n<meta name=\"twitter:site\" content=\"@OUCRU_Programme\" \/>\n<meta name=\"twitter:label1\" content=\"Ditulis oleh\" \/>\n\t<meta name=\"twitter:data1\" content=\"Chi Ngo Huyen\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimasi waktu membaca\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 menit\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/\"},\"author\":{\"name\":\"Chi Ngo Huyen\",\"@id\":\"https:\/\/www.oucru.org\/id\/#\/schema\/person\/aa112afe961656747e505d29ce550b57\"},\"headline\":\"World Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C\",\"datePublished\":\"2022-07-21T06:41:58+00:00\",\"dateModified\":\"2023-10-09T08:40:21+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/\"},\"wordCount\":658,\"publisher\":{\"@id\":\"https:\/\/www.oucru.org\/id\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2022\/07\/Stakeholder-meeting-with-NGOs-October-2021.jpg\",\"keywords\":[\"News\"],\"articleSection\":[\"News\"],\"inLanguage\":\"id\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/\",\"url\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/\",\"name\":\"World Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C - OUCRU\",\"isPartOf\":{\"@id\":\"https:\/\/www.oucru.org\/id\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2022\/07\/Stakeholder-meeting-with-NGOs-October-2021.jpg\",\"datePublished\":\"2022-07-21T06:41:58+00:00\",\"dateModified\":\"2023-10-09T08:40:21+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#breadcrumb\"},\"inLanguage\":\"id\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"id\",\"@id\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#primaryimage\",\"url\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2022\/07\/Stakeholder-meeting-with-NGOs-October-2021.jpg\",\"contentUrl\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2022\/07\/Stakeholder-meeting-with-NGOs-October-2021.jpg\",\"width\":4032,\"height\":2268,\"caption\":\"Stakeholders mapping meeting with members of community-based organizations representing and supporting underserved communities at risk of Hep C in HCMC | Bu\u1ed5i h\u1ecdp nh\u1eb1m x\u00e1c \u0111\u1ecbnh c\u00e1c b\u00ean li\u00ean quan v\u1edbi s\u1ef1 tham gia t\u1eeb c\u00e1c t\u1ed5 ch\u1ee9c c\u1ed9ng \u0111\u1ed3ng \u0111\u1ea1i di\u1ec7n v\u00e0 h\u1ed7 tr\u1ee3 cho c\u00e1c nh\u00f3m d\u1ec5 b\u1ecb t\u1ed5n th\u01b0\u01a1ng c\u00f3 nguy c\u01a1 m\u1eafc Vi\u00eam Gan C t\u1ea1i Tp.HCM\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.oucru.org\/id\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"World Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.oucru.org\/id\/#website\",\"url\":\"https:\/\/www.oucru.org\/id\/\",\"name\":\"OUCRU\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.oucru.org\/id\/#organization\"},\"alternateName\":\"Oxford University Clinical Research Unit (OUCRU)\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.oucru.org\/id\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"id\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.oucru.org\/id\/#organization\",\"name\":\"Oxford University Clinical Research Unit.\",\"alternateName\":\"OUCRU\",\"url\":\"https:\/\/www.oucru.org\/id\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"id\",\"@id\":\"https:\/\/www.oucru.org\/id\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2023\/02\/cropped-cropped-oucru-logo.png\",\"contentUrl\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2023\/02\/cropped-cropped-oucru-logo.png\",\"width\":512,\"height\":333,\"caption\":\"Oxford University Clinical Research Unit.\"},\"image\":{\"@id\":\"https:\/\/www.oucru.org\/id\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/OUCRUVN\/\",\"https:\/\/x.com\/OUCRU_Programme\",\"https:\/\/www.linkedin.com\/company\/oucru\/\",\"https:\/\/www.youtube.com\/@oxforduniversityclinicalre6618\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.oucru.org\/id\/#\/schema\/person\/aa112afe961656747e505d29ce550b57\",\"name\":\"Chi Ngo Huyen\",\"url\":\"https:\/\/www.oucru.org\/id\/author\/chinh\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"World Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C - OUCRU","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/","og_locale":"id_ID","og_type":"article","og_title":"World Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C - OUCRU","og_description":"July 28 is World Hepatitis Day. According to the World Health Organisation, 10 \u2013 15 per cent of Vietnam\u2019s population is estimated to have viral hepatitis, including 1,07 million people […]","og_url":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/","og_site_name":"OUCRU","article_publisher":"https:\/\/www.facebook.com\/OUCRUVN\/","article_published_time":"2022-07-21T06:41:58+00:00","article_modified_time":"2023-10-09T08:40:21+00:00","og_image":[{"width":4032,"height":2268,"url":"https:\/\/www.oucru.org\/wp-content\/uploads\/2022\/07\/Stakeholder-meeting-with-NGOs-October-2021.jpg","type":"image\/jpeg"}],"author":"Chi Ngo Huyen","twitter_card":"summary_large_image","twitter_creator":"@OUCRU_Programme","twitter_site":"@OUCRU_Programme","twitter_misc":{"Ditulis oleh":"Chi Ngo Huyen","Estimasi waktu membaca":"4 menit"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#article","isPartOf":{"@id":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/"},"author":{"name":"Chi Ngo Huyen","@id":"https:\/\/www.oucru.org\/id\/#\/schema\/person\/aa112afe961656747e505d29ce550b57"},"headline":"World Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C","datePublished":"2022-07-21T06:41:58+00:00","dateModified":"2023-10-09T08:40:21+00:00","mainEntityOfPage":{"@id":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/"},"wordCount":658,"publisher":{"@id":"https:\/\/www.oucru.org\/id\/#organization"},"image":{"@id":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#primaryimage"},"thumbnailUrl":"https:\/\/www.oucru.org\/wp-content\/uploads\/2022\/07\/Stakeholder-meeting-with-NGOs-October-2021.jpg","keywords":["News"],"articleSection":["News"],"inLanguage":"id"},{"@type":"WebPage","@id":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/","url":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/","name":"World Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C - OUCRU","isPartOf":{"@id":"https:\/\/www.oucru.org\/id\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#primaryimage"},"image":{"@id":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#primaryimage"},"thumbnailUrl":"https:\/\/www.oucru.org\/wp-content\/uploads\/2022\/07\/Stakeholder-meeting-with-NGOs-October-2021.jpg","datePublished":"2022-07-21T06:41:58+00:00","dateModified":"2023-10-09T08:40:21+00:00","breadcrumb":{"@id":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#breadcrumb"},"inLanguage":"id","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.oucru.org\/id\/world-hepatitis-day\/"]}]},{"@type":"ImageObject","inLanguage":"id","@id":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#primaryimage","url":"https:\/\/www.oucru.org\/wp-content\/uploads\/2022\/07\/Stakeholder-meeting-with-NGOs-October-2021.jpg","contentUrl":"https:\/\/www.oucru.org\/wp-content\/uploads\/2022\/07\/Stakeholder-meeting-with-NGOs-October-2021.jpg","width":4032,"height":2268,"caption":"Stakeholders mapping meeting with members of community-based organizations representing and supporting underserved communities at risk of Hep C in HCMC | Bu\u1ed5i h\u1ecdp nh\u1eb1m x\u00e1c \u0111\u1ecbnh c\u00e1c b\u00ean li\u00ean quan v\u1edbi s\u1ef1 tham gia t\u1eeb c\u00e1c t\u1ed5 ch\u1ee9c c\u1ed9ng \u0111\u1ed3ng \u0111\u1ea1i di\u1ec7n v\u00e0 h\u1ed7 tr\u1ee3 cho c\u00e1c nh\u00f3m d\u1ec5 b\u1ecb t\u1ed5n th\u01b0\u01a1ng c\u00f3 nguy c\u01a1 m\u1eafc Vi\u00eam Gan C t\u1ea1i Tp.HCM"},{"@type":"BreadcrumbList","@id":"https:\/\/www.oucru.org\/id\/world-hepatitis-day\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.oucru.org\/id\/"},{"@type":"ListItem","position":2,"name":"World Hepatitis Day: OUCRU research seeks to lower cost of treatment and improve access to care for patients with Hepatitis C"}]},{"@type":"WebSite","@id":"https:\/\/www.oucru.org\/id\/#website","url":"https:\/\/www.oucru.org\/id\/","name":"OUCRU","description":"","publisher":{"@id":"https:\/\/www.oucru.org\/id\/#organization"},"alternateName":"Oxford University Clinical Research Unit (OUCRU)","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.oucru.org\/id\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"id"},{"@type":"Organization","@id":"https:\/\/www.oucru.org\/id\/#organization","name":"Oxford University Clinical Research Unit.","alternateName":"OUCRU","url":"https:\/\/www.oucru.org\/id\/","logo":{"@type":"ImageObject","inLanguage":"id","@id":"https:\/\/www.oucru.org\/id\/#\/schema\/logo\/image\/","url":"https:\/\/www.oucru.org\/wp-content\/uploads\/2023\/02\/cropped-cropped-oucru-logo.png","contentUrl":"https:\/\/www.oucru.org\/wp-content\/uploads\/2023\/02\/cropped-cropped-oucru-logo.png","width":512,"height":333,"caption":"Oxford University Clinical Research Unit."},"image":{"@id":"https:\/\/www.oucru.org\/id\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/OUCRUVN\/","https:\/\/x.com\/OUCRU_Programme","https:\/\/www.linkedin.com\/company\/oucru\/","https:\/\/www.youtube.com\/@oxforduniversityclinicalre6618"]},{"@type":"Person","@id":"https:\/\/www.oucru.org\/id\/#\/schema\/person\/aa112afe961656747e505d29ce550b57","name":"Chi Ngo Huyen","url":"https:\/\/www.oucru.org\/id\/author\/chinh\/"}]}},"_links":{"self":[{"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/posts\/7913","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/users\/28"}],"replies":[{"embeddable":true,"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/comments?post=7913"}],"version-history":[{"count":2,"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/posts\/7913\/revisions"}],"predecessor-version":[{"id":33491,"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/posts\/7913\/revisions\/33491"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/media\/7915"}],"wp:attachment":[{"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/media?parent=7913"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/categories?post=7913"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.oucru.org\/id\/wp-json\/wp\/v2\/tags?post=7913"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}