{"id":46969,"date":"2025-05-12T13:46:36","date_gmt":"2025-05-12T06:46:36","guid":{"rendered":"https:\/\/www.oucru.org\/nghien-cuu-moi-mo-ra-huong-dieu-tri-viem-gan-c-hieu-qua-va-tiet-kiem-hon\/"},"modified":"2025-05-15T12:55:34","modified_gmt":"2025-05-15T05:55:34","slug":"nghien-cuu-moi-mo-ra-huong-dieu-tri-viem-gan-c-hieu-qua-va-tiet-kiem-hon","status":"publish","type":"post","link":"https:\/\/www.oucru.org\/vi\/nghien-cuu-moi-mo-ra-huong-dieu-tri-viem-gan-c-hieu-qua-va-tiet-kiem-hon\/","title":{"rendered":"Nghi\u00ean c\u1ee9u m\u1edbi m\u1edf ra h\u01b0\u1edbng \u0111i\u1ec1u tr\u1ecb vi\u00eam gan C hi\u1ec7u qu\u1ea3 v\u00e0 ti\u1ebft ki\u1ec7m h\u01a1n"},"content":{"rendered":"\n<ul class=\"wp-block-list\">\n<li>Th\u1eed nghi\u1ec7m VIETNARMS ch\u1ee9ng minh sofosbuvir\/daclatasvir (SOF\/DCV), hai lo\u1ea1i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb vi\u00eam gan C ph\u1ed5 bi\u1ebfn v\u00e0 c\u00f3 gi\u00e1 c\u1ea3 ph\u1ea3i ch\u0103ng, \u0111\u1ea1t t\u1ef7 l\u1ec7 ch\u1eefa kh\u1ecfi tr\u00ean 95%.<\/li>\n\n\n\n<li>Th\u1eed nghi\u1ec7m ch\u1ee9ng minh r\u1eb1ng 4 ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb, bao g\u1ed3m ph\u00e1c \u0111\u1ed3 r\u00fat ng\u1eafn tu\u1ef3 theo \u0111\u00e1p \u1ee9ng thu\u1ed1c, v\u1eabn c\u00f3 hi\u1ec7u qu\u1ea3 cao trong khi c\u00f3 th\u1ec3 gi\u1ea3m m\u1ed9t n\u1eeda chi ph\u00ed so v\u1edbi ph\u00e1c \u0111\u1ed3 12 tu\u1ea7n ti\u00eau chu\u1ea9n v\u1edbi chi ph\u00ed kho\u1ea3ng 33 tri\u1ec7u \u0111\u1ed3ng. <\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe title=\"The VIETNARMS Trial - Documentary\" width=\"800\" height=\"450\" src=\"https:\/\/www.youtube.com\/embed\/626n_qcSMeM?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>Vi\u00eam gan C l\u00e0 m\u1ed9t m\u1ed1i quan t\u00e2m v\u1ec1 s\u1ee9c kh\u1ecfe to\u00e0n c\u1ea7u, \u01b0\u1edbc t\u00ednh c\u00f3 58 tri\u1ec7u ng\u01b0\u1eddi b\u1ecb b\u1ec7nh m\u00e3n t\u00ednh, d\u1eabn \u0111\u1ebfn x\u01a1 gan v\u00e0 ung th\u01b0 gan. <a href=\"https:\/\/www.who.int\/health-topics\/hepatitis#tab=tab_1\" target=\"_blank\" rel=\"noreferrer noopener\">T\u1ed5 ch\u1ee9c Y t\u1ebf Th\u1ebf gi\u1edbi (WHO)<\/a> \u0111\u1eb7t m\u1ee5c ti\u00eau lo\u1ea1i b\u1ecf vi\u00eam gan si\u00eau vi t\u1eeb nay cho t\u1edbi n\u0103m 2030. T\u00ecm ra ph\u01b0\u01a1ng \u00e1n \u0111i\u1ec1u tr\u1ecb hi\u1ec7u qu\u1ea3 l\u00e0 r\u1ea5t quan tr\u1ecdng trong chi\u1ebfn l\u01b0\u1ee3c n\u00e0y c\u1ee7a WHO. M\u1eb7c d\u00f9 c\u00e1c lo\u1ea1i thu\u1ed1c kh\u00e1ng virus t\u00e1c d\u1ee5ng tr\u1ef1c ti\u1ebfp (DAA) hi\u1ec7u qu\u1ea3 cao trong \u0111i\u1ec1u tr\u1ecb Vi\u00eam gan C, c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y v\u1eabn ch\u01b0a \u0111\u01b0\u1ee3c ph\u1ed5 bi\u1ebfn r\u1ed9ng r\u00e3i v\u00e0 hi\u1ec7n nay gi\u00e1 th\u00e0nh v\u1eabn \u0111\u1eaft \u0111\u1ecf, \u0111\u1eb7c bi\u1ec7t l\u00e0 \u1edf c\u00e1c n\u01b0\u1edbc c\u00f3 thu nh\u1eadp th\u1ea5p v\u00e0 trung b\u00ecnh (LMIC) nh\u01b0 Vi\u1ec7t Nam.<\/p>\n\n\n\n<p>Hi\u1ec7n t\u1ea1i, ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb ti\u00eau chu\u1ea9n cho vi\u00eam gan C k\u00e9o d\u00e0i 12 tu\u1ea7n v\u1edbi chi ph\u00ed kho\u1ea3ng 33 tri\u1ec7u \u0111\u1ed3ng, trong \u0111\u00f3 b\u1ea3o hi\u1ec3m x\u00e3 h\u1ed9i ch\u1ec9 chi tr\u1ea3 50%. Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb k\u00e9o d\u00e0i v\u00e0 chi ph\u00ed cao c\u00f3 th\u1ec3 khi\u1ebfn b\u1ec7nh nh\u00e2n ch\u1ecdn ph\u01b0\u01a1ng \u00e1n kh\u00f4ng \u0111i\u1ec1u tr\u1ecb, ho\u1eb7c b\u1ecf gi\u1eefa ch\u1eebng. <\/p>\n\n\n\n<p>Th\u1eed nghi\u1ec7m VIETNARMS, \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n t\u1eeb n\u0103m 2018 \u0111\u1ebfn n\u0103m 2024 v\u1edbi 624 b\u1ec7nh nh\u00e2n tham gia, \u0111\u00e3 so s\u00e1nh tr\u1ef1c ti\u1ebfp hai ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb vi\u00eam gan C \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i: sofosbuvir\/daclatasvir (SOF\/DCV) v\u00e0 sofosbuvir\/velpatasvir (SOF\/VEL). Th\u1eed nghi\u1ec7m cho th\u1ea5y SOF\/DCV cho th\u1ea5y t\u1ef7 l\u1ec7 ch\u1eefa kh\u1ecfi cao h\u01a1n so v\u1edbi SOF\/VEL. Ph\u00e1t hi\u1ec7n n\u00e0y \u0111\u1eb7c bi\u1ec7t c\u00f3 \u00fd ngh\u0129a \u0111\u1ed1i v\u1edbi c\u00e1c n\u01b0\u1edbc c\u00f3 thu nh\u1eadp th\u1ea5p v\u00e0 trung b\u00ecnh nh\u01b0 Vi\u1ec7t Nam, do hai lo\u1ea1i thu\u1ed1c SOF\/DCV d\u1ec5 ti\u1ebfp c\u1eadn v\u00e0 gi\u00e1 c\u1ea3 ph\u1ea3i ch\u0103ng h\u01a1n. <\/p>\n\n\n\n<p>Ngo\u00e0i vi\u1ec7c so s\u00e1nh c\u00e1c lo\u1ea1i thu\u1ed1c hi\u1ec7n c\u00f3, th\u1eed nghi\u1ec7m VIETNARMS \u0111\u00e3 t\u00ecm ra c\u00e1c ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb m\u1edbi \u0111\u1ec3 gi\u00fap t\u0103ng kh\u1ea3 n\u0103ng ti\u1ebfp c\u1eadn v\u00e0 kh\u1ea3 n\u0103ng chi tr\u1ea3 cho b\u1ec7nh nh\u00e2n. Trong 4 nh\u00e1nh, ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb \u0111i\u1ec1u ch\u1ec9nh theo \u0111\u00e1p \u1ee9ng thu\u1ed1c c\u1ee7a t\u1eebng b\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 r\u00fat ng\u1eafn th\u1eddi gian \u0111i\u1ec1u tr\u1ecb xu\u1ed1ng c\u00f2n 4 tu\u1ea7n, v\u1edbi chi ph\u00ed gi\u1ea3m \u0111i m\u1ed9t n\u1eeda m\u00e0 v\u1eabn \u0111\u1ea3m b\u1ea3o hi\u1ec7u qu\u1ea3 t\u01b0\u01a1ng \u0111\u01b0\u01a1ng. <\/p>\n\n\n\n<p>Nh\u1eefng ph\u00e1t hi\u1ec7n n\u00e0y cung c\u1ea5p b\u1eb1ng ch\u1ee9ng gi\u00fap m\u1edf r\u1ed9ng kh\u1ea3 n\u0103ng ti\u1ebfp c\u1eadn \u0111i\u1ec1u tr\u1ecb, \u0111\u1eb7c bi\u1ec7t l\u00e0 cho c\u00e1c c\u1ed9ng \u0111\u1ed3ng d\u1ec5 b\u1ecb t\u1ed5n th\u01b0\u01a1ng v\u00e0 kh\u00f3 ti\u1ebfp c\u1eadn. K\u1ebft qu\u1ea3 c\u1ee7a th\u1eed nghi\u1ec7m n\u00e0y c\u00f3 kh\u1ea3 n\u0103ng \u0111\u1ecbnh h\u00ecnh c\u00e1c h\u01b0\u1edbng d\u1eabn \u0111i\u1ec1u tr\u1ecb Vi\u00eam gan C tr\u00ean to\u00e0n th\u1ebf gi\u1edbi.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><a href=\"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/05\/2.png\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/05\/2-1024x576.png\" alt=\"\" class=\"wp-image-46955\" style=\"width:802px;height:auto\" srcset=\"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/05\/2-1024x576.png 1024w, https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/05\/2-300x169.png 300w, https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/05\/2-768x432.png 768w, https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/05\/2-1536x864.png 1536w, https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/05\/2.png 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/a><figcaption class=\"wp-element-caption\">B\u1ea3ng: So s\u00e1nh 4 ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb <\/figcaption><\/figure>\n\n\n\n<p>Th\u1eed nghi\u1ec7m n\u00e0y l\u00e0 h\u1ee3p t\u00e1c \u0111a qu\u1ed1c gia gi\u1eefa \u0110\u1ea1i h\u1ecdc Ho\u00e0ng gia London, \u0110\u1ea1i h\u1ecdc Oxford, OUCRU, c\u0169ng nh\u01b0 c\u00e1c \u0111\u1ed1i t\u00e1c \u0111\u1ecba ph\u01b0\u01a1ng t\u1ea1i Vi\u1ec7t Nam bao g\u1ed3m B\u1ec7nh vi\u1ec7n B\u1ec7nh Nhi\u1ec7t \u0111\u1edbi Tp. H\u1ed3 Ch\u00ed Minh, B\u1ec7nh vi\u1ec7n B\u1ec7nh Nhi\u1ec7t \u0111\u1edbi Trung \u01b0\u01a1ng H\u00e0 N\u1ed9i, CDC H\u00e0 Nam, CDC H\u00e0 N\u1ed9i, c\u00e1c b\u1ec7nh vi\u1ec7n khu v\u1ef1c v\u00e0 c\u00e1c t\u1ed5 ch\u1ee9c c\u1ed9ng \u0111\u1ed3ng.<\/p>\n\n\n\n<p>Ch\u1ee7 nhi\u1ec7m \u0111\u1ec1 t\u00e0i, Gi\u00e1o s\u01b0 Graham Cooke chia s\u1ebb: &#8220;M\u1eb7c d\u00f9 ghi nh\u1eadn m\u1ed9t s\u1ed1 quan ng\u1ea1i ban \u0111\u1ea7u, d\u1eef li\u1ec7u t\u1eeb nghi\u00ean c\u1ee9u cho th\u1ea5y ph\u00e1c \u0111\u1ed3 SOF\/DCV hi\u1ec7u qu\u1ea3 v\u00e0 ph\u00f9 h\u1ee3p \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb vi\u00eam gan C t\u1ea1i Vi\u1ec7t Nam. Ph\u00e1c \u0111\u1ed3 v\u1edbi chi ph\u00ed ph\u1ea3i ch\u0103ng n\u00e0y c\u00f3 th\u1ec3 g\u00f3p ph\u1ea7n m\u1edf r\u1ed9ng kh\u1ea3 n\u0103ng ti\u1ebfp c\u1eadn \u0111i\u1ec1u tr\u1ecb cho nhi\u1ec1u b\u1ec7nh nh\u00e2n, t\u1eeb \u0111\u00f3 th\u00fac \u0111\u1ea9y m\u1ee5c ti\u00eau lo\u1ea1i tr\u1eeb c\u0103n b\u1ec7nh nguy hi\u1ec3m n\u00e0y.&#8221;<\/p>\n\n\n\n<p>Ti\u1ebfn s\u0129, B\u00e1c s\u0129 Nguy\u1ec5n V\u0103n V\u0129nh Ch\u00e2u, Ph\u00f3 Gi\u00e1m \u0111\u1ed1c S\u1edf Y t\u1ebf Th\u00e0nh ph\u1ed1 H\u1ed3 Ch\u00ed Minh cho bi\u1ebft: \u201cK\u1ebft qu\u1ea3 nghi\u00ean c\u1ee9u n\u00e0y l\u00e0 ti\u1ec1n \u0111\u1ec1 gi\u00fap T\u1ed5 ch\u1ee9c Y t\u1ebf Th\u1ebf gi\u1edbi v\u00e0 B\u1ed9 Y t\u1ebf Vi\u1ec7t Nam c\u00f3 th\u1ec3 \u0111i\u1ec1u ch\u1ec9nh, c\u1eadp nh\u1eadt ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb vi\u00eam gan C. Nh\u1edd \u0111\u00f3, ch\u00fang ta c\u00f3 c\u01a1 h\u1ed9i r\u00fat ng\u1eafn th\u1eddi gian \u0111i\u1ec1u tr\u1ecb, s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p c\u00e1c lo\u1ea1i thu\u1ed1c hi\u1ec7u qu\u1ea3 v\u1edbi chi ph\u00ed h\u1ee3p l\u00fd h\u01a1n.&#8221;&nbsp;&nbsp;<\/p>\n\n\n\n<p>Th\u1eed nghi\u1ec7m VIETNARMS, v\u1edbi thi\u1ebft k\u1ebf nghi\u00eam ng\u1eb7t v\u00e0 \u0111\u00e1nh gi\u00e1 to\u00e0n di\u1ec7n c\u1ea3 ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb truy\u1ec1n th\u1ed1ng v\u00e0 ph\u00e1c \u0111\u1ed3 m\u1edbi, l\u00e0 m\u1ed9t b\u01b0\u1edbc ti\u1ebfn \u0111\u00e1ng k\u1ec3 trong cu\u1ed9c chi\u1ebfn ch\u1ed1ng l\u1ea1i vi\u00eam gan C. Nh\u1eefng ph\u00e1t hi\u1ec7n c\u1ee7a nghi\u00ean c\u1ee9u c\u00f3 kh\u1ea3 n\u0103ng \u0111\u1ecbnh h\u00ecnh c\u00e1c h\u01b0\u1edbng d\u1eabn \u0111i\u1ec1u tr\u1ecb, cung c\u1ea5p th\u00f4ng tin cho c\u00e1c ch\u00ednh s\u00e1ch ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe v\u1edbi hy v\u1ecdng c\u1ea3i thi\u1ec7n cu\u1ed9c s\u1ed1ng c\u1ee7a h\u00e0ng tri\u1ec7u ng\u01b0\u1eddi b\u1ecb \u1ea3nh h\u01b0\u1edfng b\u1edfi c\u0103n b\u1ec7nh n\u00e0y.&nbsp;&nbsp;<\/p>\n\n\n\n<p>\u0110\u1ec3 t\u00ecm hi\u1ec3u th\u00eam v\u1ec1 k\u1ebft qu\u1ea3,<a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(25)00097-2\/fulltext\">&nbsp;h\u00e3y truy c\u1eadp b\u00e0i b\u00e1o t\u1ea1i \u0111\u00e2y<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0110\u01a1n v\u1ecb Nghi\u00ean c\u1ee9u L\u00e2m s\u00e0ng \u0110\u1ea1i h\u1ecdc Oxford (OUCRU) \u0111\u00e3 c\u00f4ng b\u1ed1 k\u1ebft qu\u1ea3 \u0111\u1ea7y h\u1ee9a h\u1eb9n t\u1eeb th\u1eed nghi\u1ec7m VIETNARMS, m\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u0111a nh\u00e1nh \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n t\u1ea1i Vi\u1ec7t Nam. K\u1ebft qu\u1ea3 ch\u1ee9ng minh ti\u1ec1m n\u0103ng c\u1ee7a c\u00e1c ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb m\u1edbi cho vi\u00eam gan C, c\u00f3 kh\u1ea3 n\u0103ng gi\u1ea3m th\u1eddi gian v\u00e0 chi ph\u00ed \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n. <\/p>\n","protected":false},"author":39,"featured_media":46928,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":"","_wp_rev_ctl_limit":""},"categories":[291],"tags":[219],"class_list":["post-46969","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-oucru-ho-chi-minh","tag-noi-bat"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.3.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Nghi\u00ean c\u1ee9u m\u1edbi m\u1edf ra h\u01b0\u1edbng \u0111i\u1ec1u tr\u1ecb vi\u00eam gan C hi\u1ec7u qu\u1ea3 v\u00e0 ti\u1ebft ki\u1ec7m h\u01a1n - OUCRU<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.oucru.org\/vi\/nghien-cuu-moi-mo-ra-huong-dieu-tri-viem-gan-c-hieu-qua-va-tiet-kiem-hon\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nghi\u00ean c\u1ee9u m\u1edbi m\u1edf ra h\u01b0\u1edbng \u0111i\u1ec1u tr\u1ecb vi\u00eam gan C hi\u1ec7u qu\u1ea3 v\u00e0 ti\u1ebft ki\u1ec7m h\u01a1n - OUCRU\" \/>\n<meta property=\"og:description\" content=\"\u0110\u01a1n v\u1ecb Nghi\u00ean c\u1ee9u L\u00e2m s\u00e0ng \u0110\u1ea1i h\u1ecdc Oxford (OUCRU) \u0111\u00e3 c\u00f4ng b\u1ed1 k\u1ebft qu\u1ea3 \u0111\u1ea7y h\u1ee9a h\u1eb9n t\u1eeb th\u1eed nghi\u1ec7m VIETNARMS, m\u1ed9t th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng \u0111a nh\u00e1nh \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n t\u1ea1i Vi\u1ec7t Nam. 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