{"id":52258,"date":"2025-08-11T11:11:18","date_gmt":"2025-08-11T04:11:18","guid":{"rendered":"https:\/\/www.oucru.org\/?p=52258"},"modified":"2025-08-11T11:11:23","modified_gmt":"2025-08-11T04:11:23","slug":"indonesia-to-host-first-dual-species-malaria-vaccination-trial","status":"publish","type":"post","link":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/","title":{"rendered":"Indonesia to Host First Dual-Species Malaria Vaccination Trial"},"content":{"rendered":"\n

OUCRU Indonesia is preparing a Phase 2 clinical trial of a malaria vaccination designed to protect against the two most widespread malaria parasites, Plasmodium falciparum<\/em> and Plasmodium vivax<\/em>. The trial, to be conducted in Keerom, Papua, will be the first to test a dual-species malaria vaccination in humans. <\/p>\n\n\n\n

The trial will test two vaccines developed by the Jenner Institute<\/a>: R21 for P. falciparum<\/em> and Rv21 for P. vivax<\/em>. These will be administered together as part of a multi-dose vaccination regimen. The long-term goal is to deliver protection against both species in a single vaccination, which would be a first in malaria vaccine development. <\/p>\n\n\n\n

\u201cThis is an important step toward a practical solution for countries like Indonesia,\u201d said Professor Kevin Baird<\/a>, Director of OUCRU Indonesia. \u201cA vaccination that protects against both falciparum <\/em>and vivax <\/em>malaria would be game-changing for the Asia-Pacific, where more than 80 percent of the global P. vivax<\/em> burden is concentrated.\u201d <\/p>\n\n\n\n

Dr Mehreen Datoo, a lead researcher from the Jenner Institute, visited Jakarta and Keerom last month to meet partners and review preparations for the upcoming trial. She has played a key role in the development of R21, one of only two malaria vaccines recommended by the WHO.<\/a> That recommendation is based on trials conducted in Africa and targets only P. falciparum<\/em>. There is still no licensed vaccine for P. vivax<\/em>.<\/p>\n\n\n\n

\"\"<\/a>
Dr Mehreen Datoo meets with partners in Indonesia to collaborate on the world’s first dual-species malaria vaccination trial in June 2025.<\/figcaption><\/figure>\n\n\n\n

\u201cThe R21 vaccine is already recommended by the WHO for use in children in Africa and it is important to think about extending this recommendation and where else it can be of benefit,\u201d  said Datoo. \u201cThis study will help us understand how the vaccine performs in adults in other regions, as well as explore protection against other malaria species such as P. vivax<\/em>. \u201d <\/p>\n\n\n\n

Keerom was selected as the study site due to its extraordinarily high malaria incidence. \u201cThe disease is hyperendemic in the region, causing severe illness and deaths every year,\u201d said Baird. \u201cThis makes it an ideal setting to study how a dual-species vaccination performs in real-world conditions.\u201d <\/p>\n\n\n\n

\"\"<\/a>
In February, Jenner Institute Director Professor Adrian Hill<\/a> met with Indonesia\u2019s Health Minister Budi Gunadi Sadikin to present the vaccine\u2019s global progress and propose plans for its evaluation in Indonesia. <\/figcaption><\/figure>\n\n\n\n

This phase 2 trial is planned to begin after the Rv21 Phase 1 trial in the UK concludes, expected around mid-2026. <\/p>\n\n\n\n

This will be OUCRU Indonesia\u2019s second malaria vaccine trial, following its work last year on Indonesia\u2019s first-ever malaria vaccine study<\/a>, which tested Sanaria\u00ae PfSPZ and Sanaria\u00ae PfSPZ-CVac. <\/p>\n\n\n\n

As one of Indonesia\u2019s leading research organizations on infectious diseases, OUCRU Indonesia currently leads three of the six active clinical trials in the country. <\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

OUCRU Indonesia is preparing a Phase 2 clinical trial of a malaria vaccination designed to protect against the two most widespread malaria parasites, Plasmodium falciparum and Plasmodium vivax. The trial, […]<\/p>\n","protected":false},"author":42,"featured_media":52271,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":"","_wp_rev_ctl_limit":""},"categories":[146],"tags":[33],"class_list":["post-52258","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-indonesia","tag-news"],"acf":[],"yoast_head":"\nIndonesia to Host First Dual-Species Malaria Vaccination Trial - OUCRU<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Indonesia to Host First Dual-Species Malaria Vaccination Trial - OUCRU\" \/>\n<meta property=\"og:description\" content=\"OUCRU Indonesia is preparing a Phase 2 clinical trial of a malaria vaccination designed to protect against the two most widespread malaria parasites, Plasmodium falciparum and Plasmodium vivax. The trial, […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/\" \/>\n<meta property=\"og:site_name\" content=\"OUCRU\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/OUCRUVN\/\" \/>\n<meta property=\"article:published_time\" content=\"2025-08-11T04:11:18+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-08-11T04:11:23+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/08\/IMG20250623110557-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1920\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"ipindra\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@OUCRU_Programme\" \/>\n<meta name=\"twitter:site\" content=\"@OUCRU_Programme\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ipindra\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/\"},\"author\":{\"name\":\"ipindra\",\"@id\":\"https:\/\/www.oucru.org\/vi\/#\/schema\/person\/6370f8d7ca2fe970f54522220e408381\"},\"headline\":\"Indonesia to Host First Dual-Species Malaria Vaccination Trial\",\"datePublished\":\"2025-08-11T04:11:18+00:00\",\"dateModified\":\"2025-08-11T04:11:23+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/\"},\"wordCount\":473,\"publisher\":{\"@id\":\"https:\/\/www.oucru.org\/vi\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/08\/IMG20250623110557-scaled.jpg\",\"keywords\":[\"News\"],\"articleSection\":[\"OUCRU Indonesia\"],\"inLanguage\":\"vi-VN\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/\",\"url\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/\",\"name\":\"Indonesia to Host First Dual-Species Malaria Vaccination Trial - OUCRU\",\"isPartOf\":{\"@id\":\"https:\/\/www.oucru.org\/vi\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/08\/IMG20250623110557-scaled.jpg\",\"datePublished\":\"2025-08-11T04:11:18+00:00\",\"dateModified\":\"2025-08-11T04:11:23+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#breadcrumb\"},\"inLanguage\":\"vi-VN\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"vi-VN\",\"@id\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#primaryimage\",\"url\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/08\/IMG20250623110557-scaled.jpg\",\"contentUrl\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/08\/IMG20250623110557-scaled.jpg\",\"width\":2560,\"height\":1920,\"caption\":\"oplus_137363456\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.oucru.org\/vi\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Indonesia to Host First Dual-Species Malaria Vaccination Trial\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.oucru.org\/vi\/#website\",\"url\":\"https:\/\/www.oucru.org\/vi\/\",\"name\":\"OUCRU\",\"description\":\"The Oxford University Clinical Research Unit (OUCRU) is a large-scale clinical and public health research unit with site offices in Viet Nam, Indonesia, and Nepal.\",\"publisher\":{\"@id\":\"https:\/\/www.oucru.org\/vi\/#organization\"},\"alternateName\":\"Oxford University Clinical Research Unit (OUCRU)\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.oucru.org\/vi\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"vi-VN\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.oucru.org\/vi\/#organization\",\"name\":\"Oxford University Clinical Research Unit.\",\"alternateName\":\"OUCRU\",\"url\":\"https:\/\/www.oucru.org\/vi\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"vi-VN\",\"@id\":\"https:\/\/www.oucru.org\/vi\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2023\/02\/cropped-cropped-oucru-logo.png\",\"contentUrl\":\"https:\/\/www.oucru.org\/wp-content\/uploads\/2023\/02\/cropped-cropped-oucru-logo.png\",\"width\":512,\"height\":333,\"caption\":\"Oxford University Clinical Research Unit.\"},\"image\":{\"@id\":\"https:\/\/www.oucru.org\/vi\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/OUCRUVN\/\",\"https:\/\/x.com\/OUCRU_Programme\",\"https:\/\/www.linkedin.com\/company\/oucru\/\",\"https:\/\/www.youtube.com\/@oxforduniversityclinicalre6618\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.oucru.org\/vi\/#\/schema\/person\/6370f8d7ca2fe970f54522220e408381\",\"name\":\"ipindra\",\"url\":\"https:\/\/www.oucru.org\/vi\/author\/ipindra\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Indonesia to Host First Dual-Species Malaria Vaccination Trial - OUCRU","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/","og_locale":"vi_VN","og_type":"article","og_title":"Indonesia to Host First Dual-Species Malaria Vaccination Trial - OUCRU","og_description":"OUCRU Indonesia is preparing a Phase 2 clinical trial of a malaria vaccination designed to protect against the two most widespread malaria parasites, Plasmodium falciparum and Plasmodium vivax. The trial, […]","og_url":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/","og_site_name":"OUCRU","article_publisher":"https:\/\/www.facebook.com\/OUCRUVN\/","article_published_time":"2025-08-11T04:11:18+00:00","article_modified_time":"2025-08-11T04:11:23+00:00","og_image":[{"width":2560,"height":1920,"url":"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/08\/IMG20250623110557-scaled.jpg","type":"image\/jpeg"}],"author":"ipindra","twitter_card":"summary_large_image","twitter_creator":"@OUCRU_Programme","twitter_site":"@OUCRU_Programme","twitter_misc":{"Written by":"ipindra","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#article","isPartOf":{"@id":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/"},"author":{"name":"ipindra","@id":"https:\/\/www.oucru.org\/vi\/#\/schema\/person\/6370f8d7ca2fe970f54522220e408381"},"headline":"Indonesia to Host First Dual-Species Malaria Vaccination Trial","datePublished":"2025-08-11T04:11:18+00:00","dateModified":"2025-08-11T04:11:23+00:00","mainEntityOfPage":{"@id":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/"},"wordCount":473,"publisher":{"@id":"https:\/\/www.oucru.org\/vi\/#organization"},"image":{"@id":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#primaryimage"},"thumbnailUrl":"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/08\/IMG20250623110557-scaled.jpg","keywords":["News"],"articleSection":["OUCRU Indonesia"],"inLanguage":"vi-VN"},{"@type":"WebPage","@id":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/","url":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/","name":"Indonesia to Host First Dual-Species Malaria Vaccination Trial - OUCRU","isPartOf":{"@id":"https:\/\/www.oucru.org\/vi\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#primaryimage"},"image":{"@id":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#primaryimage"},"thumbnailUrl":"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/08\/IMG20250623110557-scaled.jpg","datePublished":"2025-08-11T04:11:18+00:00","dateModified":"2025-08-11T04:11:23+00:00","breadcrumb":{"@id":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#breadcrumb"},"inLanguage":"vi-VN","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/"]}]},{"@type":"ImageObject","inLanguage":"vi-VN","@id":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#primaryimage","url":"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/08\/IMG20250623110557-scaled.jpg","contentUrl":"https:\/\/www.oucru.org\/wp-content\/uploads\/2025\/08\/IMG20250623110557-scaled.jpg","width":2560,"height":1920,"caption":"oplus_137363456"},{"@type":"BreadcrumbList","@id":"https:\/\/www.oucru.org\/vi\/indonesia-to-host-first-dual-species-malaria-vaccination-trial\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.oucru.org\/vi\/"},{"@type":"ListItem","position":2,"name":"Indonesia to Host First Dual-Species Malaria Vaccination Trial"}]},{"@type":"WebSite","@id":"https:\/\/www.oucru.org\/vi\/#website","url":"https:\/\/www.oucru.org\/vi\/","name":"OUCRU","description":"The Oxford University Clinical Research Unit (OUCRU) is a large-scale clinical and public health research unit with site offices in Viet Nam, Indonesia, and Nepal.","publisher":{"@id":"https:\/\/www.oucru.org\/vi\/#organization"},"alternateName":"Oxford University Clinical Research Unit (OUCRU)","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.oucru.org\/vi\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"vi-VN"},{"@type":"Organization","@id":"https:\/\/www.oucru.org\/vi\/#organization","name":"Oxford University Clinical Research Unit.","alternateName":"OUCRU","url":"https:\/\/www.oucru.org\/vi\/","logo":{"@type":"ImageObject","inLanguage":"vi-VN","@id":"https:\/\/www.oucru.org\/vi\/#\/schema\/logo\/image\/","url":"https:\/\/www.oucru.org\/wp-content\/uploads\/2023\/02\/cropped-cropped-oucru-logo.png","contentUrl":"https:\/\/www.oucru.org\/wp-content\/uploads\/2023\/02\/cropped-cropped-oucru-logo.png","width":512,"height":333,"caption":"Oxford University Clinical Research Unit."},"image":{"@id":"https:\/\/www.oucru.org\/vi\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/OUCRUVN\/","https:\/\/x.com\/OUCRU_Programme","https:\/\/www.linkedin.com\/company\/oucru\/","https:\/\/www.youtube.com\/@oxforduniversityclinicalre6618"]},{"@type":"Person","@id":"https:\/\/www.oucru.org\/vi\/#\/schema\/person\/6370f8d7ca2fe970f54522220e408381","name":"ipindra","url":"https:\/\/www.oucru.org\/vi\/author\/ipindra\/"}]}},"_links":{"self":[{"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/posts\/52258","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/users\/42"}],"replies":[{"embeddable":true,"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/comments?post=52258"}],"version-history":[{"count":2,"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/posts\/52258\/revisions"}],"predecessor-version":[{"id":52270,"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/posts\/52258\/revisions\/52270"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/media\/52271"}],"wp:attachment":[{"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/media?parent=52258"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/categories?post=52258"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.oucru.org\/vi\/wp-json\/wp\/v2\/tags?post=52258"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}