Southeast Asia Initiative to Combat SARS-CoV-2 Variants (SEACOVARIANTS)

Funder:
Wellcome

Duration:
1st November 2022 – 31st October 2025

Location of activity:
Indonesia, Singapore, Thailand, UK and Viet Nam

Principal Investigator:
Assoc. Prof. Le Van Tan

This project aims to develop and apply a multidisciplinary research platform for rapid assessment of the biological significance of SARS-CoV-2 variants, thereby supporting local policymakers with evidence-based decision-making.

A multidisciplinary research platform that would enable locally-led research response to COVID-19 pandemic and future outbreaks.

Co-Investigators

 

Southeast Asia (SEA) represents a weakness in the global COVID-19 pandemic response because many countries do not have the required capacity to conduct advanced analysis to determine the potential threat of SARS-CoV-2 variants.

A multidisciplinary research platform that would enable locally-led research response to COVID-19 pandemic and future outbreaks. This project is delivered by the Viet Nam and Thailand Wellcome Africa Asia Programmes (AAP), bringing together a multidisciplinary team in Indonesia, Thailand and Viet Nam with partners in Singapore, the UK and the US. It will strengthen regional scientific capacity that can be rapidly deployed for future outbreak responses.

Objectives:

  1. Establish a new SEA research platform that supports locally-led investigations evaluating the biology of emerging SARS-CoV-2 variants.
  2. Employ state-of-the-art structural biology to provide a rapid prediction of the ability of new variants to evade host immunity and drugs.
  3. Evaluate the impact of circulating variants of concern (VOCs) on antibody and T-cell responses in SEA populations and the clinical consequences of infection.
  4. Create a framework for effective communication and engagement with policymakers and the public concerning new virus variants and their potential to threaten public health.

 

 

PELAJARI SELENGKAPNYA

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