Abhilasha Karkey

Associate Professor Abhilasha Karkey

Director of OUCRU Nepal

Associate Professor Abhilasha Karkey is a medical microbiologist and Director of OUCRU Nepal.


Dr Abhilasha Karkey’s current research focus is on antimicrobial resistance in Gram-negative pathogens (Klebsiella pneumonia and Enterobacter spp) with a specific focus on the enteric pathogens Salmonella Typhi and Paratyphi A. She leads research studies focusing on the surveillance of resistant pathogens and works in close collaboration with hospitals to devise appropriate antimicrobial stewardship (AMS) and infection prevention-control (IPC) programs.

Of specific interest for her are the enteric fever pathogens, Salmonella Typhi and Paratyphi. In addition to monitoring the resistance in these pathogens, she is working towards the elimination of enteric fever in Nepal: could this be a case study for the elimination of other similar infectious diseases?

Career and achievements

Dr Karkey started her career with the French section of a non-profit organisation Médecins Sans Frontières, also known as Doctors Without Borders. She has a decade of experience working with MSF, managing infectious diseases, often in conflict areas all over Africa and Asia.

She has extensive experience in setting up field diagnostic laboratories and blood banks. On completion of her master’s degree in medical microbiology at the Liverpool School of Tropical Medicine and Hygiene, she returned to Nepal and started her career with OUCRU Nepal as a researcher and simultaneously enrolled for a DPhil degree with the Nuffield Department of Medicine at the University of Oxford. She won the prestigious NDM graduate prize for her thesis, which she completed in 2012.

She currently sits on the boards of the Fleming Fund Technical Advisory Group and the WHO’s Expert Working Group on Enteric Fever. She is also part of Wellcome’s inclusive research design practices (IRDP) project as part of the expert advisory group.

Professional memberships

  • American Society of Tropical Medicine and Hygiene (ASTMH)
  • Royal Society of Tropical Medicine and Hygiene (RSTMH)
  • American Society for Microbiology (ASM)




Appointed as Director of the Oxford University Clinical Research Unit Nepal


Became the Alan J Magill Fellow and an Aspen New Voices Fellow. 


Appointed as Vice Director of the Oxford University Clinical Research Unit Nepal


Became an OAK Foundation Scientific Leader Fellow


Completed DPhil and awarded the Nuffield Department of Medicines’ graduate prize


Seminal work on the epidemiology of Salmonella Typhi in Nepal looking at geospatial analysis revealing modes of endemic urban typhoid fever transmission.


Started working with the Oxford University Clinical Research Unit Nepal in Patan Hospital as a DPhil student


GRAM Typhoid Collaborators
Lancet Glob Health
March 1, 2024
DOI: 10.1016/S2214-109X(23)00585-5
RECOVERY Collaborative Group; Peter W Horby, Leon Peto, Natalie Staplin, Mark Campbell, Guilherme Pessoa-Amorim, Marion Mafham, Jonathan R Emberson, Richard Stewart, Benjamin Prudon, Alison Uriel, Christopher A Green, Devesh J Dhasmana, Flora Malein, Jaydip Majumdar, Paul Collini, Jack Shurmer, Bryan Yates, J Kenneth Baillie, Maya H Buch, Jeremy Day, Saul N Faust, Thomas Jaki, Katie Jeffer, Edmund Juszczak, Marian Knight, Wei Shen Lim, Alan Montgomery, Andrew Mumford, Kathryn Rowan, Guy Thwaites, Richard Haynes, Martin J Landray
Nat Commun
January 31, 2024
DOI: 10.1038/s41467-023-43644-x
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