Projects

This project aims to roll out clinical AMR surveillance as part of routine care in a network of hospitals across Asia and Africa and to collect microbiology and clinical data from 2,500 patients per site, which will expand on the sample-based approach of WHO GLASS and enable classification of infection syndromes, the origin of infection and outcome.

This project aims to conduct a nationwide assessment of the current state of implementation of hospital ASPs across all 37 provinces to inform stakeholders on the current stage of AMS implementation, their barriers and enablers, and to estimate the impact of COVID-19 at a local level.

This study helps identify factors associated with multidrug-resistant tuberculosis (MDR-TB) treatment success and will significantly contribute to the evidence base for the development of MDR-TB treatment regimens in the MDR-TB management programme in Vietnam.

This study aims to investigate the causes of the substantial heterogeneity in treatment responses and outcomes from drug-susceptible pulmonary tuberculosis.

ABACUS phase I (2016-2019) explored antibiotic use and access practices in 6 LMICs and revealed the importance of a context and cultural tailored approach to address responsible antibiotic use in each country. ABACUS phase II (2020-) builds on findings from phase I and aims to investigate the idea of an harmonised physical appearance of antibiotics to facilitate identification from patients and health care professionals.

ACT HIV is a parallel-group, randomised (1:1), double-blind, placebo-controlled multi-centre Phase III trial comparing dexamethasone versus placebo for 6–8 weeks in addition to standard anti-tuberculosis and antiretroviral treatment.

Analyses of correlates of SARS-CoV-2 infection or mortality have usually assessed individual predictors. This study aimed to determine if patterns of combined predictors may better identify risk of infection and mortality.

This project aims to compare the impact of a package of interventions on clinical outcomes and antibiotic prescriptions.

This project aims to provide proof of principle that a team within a low- and middle-income setting can set up a unique remote monitoring platform during a pandemic that will immediately aid clinical care and capture data for innovative research methodologies that improve clinical outcomes.

This study will provide insights into AMR gene diversity and the duration of AMR colonization in the gastrointestinal tract of young children in Vietnam.

This study aims to identify and explore known and unknown barriers and facilitators to adopting BC sampling recommendations in Indonesia, Thailand and Viet Nam.