The Bacterial Etiology And Antimicrobial Susceptibility Patterns Of Lower Respiratory And Intra-Abdominal Infections In Vietnam


Principal Investigator 
Associate Professor Rogier van Doorn
Dr Pham Thanh Duy

Dr. Nguyen Phu Huong Lan (Hospital for Tropical Diseases)
Truong Thien Phu (Cho Ray Hospital)
Nguyen Su Minh Tuyet (Gia Dinh People’s Hospital)
Nguyen Hong Nhung (Bach Mai Hospital)
Van Dinh Trang (National Hospital for Tropical Diseases)
Nguyen Thi Van (Viet-German Hospital)

This study is multi-hospital surveillance of key pathogens causing lower respiratory and intra-abdominal infections in Vietnam.

The study will determine the AMR profile and AMR genes (cephalosporins, carbapenems, vancomycin, methicillin) of predominant Gram-negative and Gram-positive bacterial pathogens obtained from patients with the two clinical syndromes.

We will also perform in vitro testing of new antimicrobials (ceftazidime-avibactam, ceftolozane-tazobactam) against carbapenem-resistant Gram-negative organisms exhibiting distinct resistance mechanisms, as well as testing for ceftaroline against MRSA. Data from our study has major country-wide implications in guiding new treatment regimens for MDR organisms associated with lower respiratory and intra-abdominal infections.

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