Senior Clinical Fellow, Emerging Infections

Associate Professor C. Louise Thwaites

Senior Clinical Research Fellow

Louise Thwaites’ research interests are centred on the care of critically ill patients in resource-restricted settings, including introducing new technologies to address these challenges.

Louise Thwaites is a clinical researcher and member of the Emerging Infections group at OUCRU. She is an Associate Professor in the Centre for Tropical Medicine and Global Health at the University of Oxford.

She is an expert consultant to the World Health Organization and a member of the sepsis in resource-limited settings–expert consensus recommendations group of the European Society of Intensive Care Medicine and CRITICal CARE Asia (Collaboration for Research, Implementation & Training in Intensive CARE in Asia). Louise is a member of the steering committee of the Asia Pacific Sepsis Association and leads the guidelines, policy and quality working group.

She has spent much of her career engaged in research into tetanus. This includes conducting a large randomized controlled trial of magnesium sulphate in tetanus, investigation into the underlying pathophysiology and long-term outcome following tetanus and, more recently, trying to understand which populations are most at risk of tetanus and ways to improve vaccination uptake in these communities.

Her broader research interests also include the management of sepsis and septic shock in resource-limited settings and understanding and preventing hospital-acquired infection in the intensive care unit. She is interested in ways of improving the care of critically ill patients using new technologies.

Her current role in the VITAL project involves developing new devices and technologies for use in diagnosis, treatment and rehabilitation following diseases such as tetanus, sepsis and dengue.

Publications

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Angela McBride, Nguyen Lam Vuong, Nguyen Van Hao, Nguyen Quang Huy, Ho Quang Chanh, Nguyen Thi Xuan Chau, Nguyen Minh Nguyet, Damien K Ming, Nguyen Thanh Ngoc Phung Tran Huy Nhat, Nguyen Thanh Phong, Luong Thi Hue Tai, Phan Vinh Tho, Dinh The Trung, Dong Thi Hoai Tam, Huynh Trung Trieu, Ronald Bertus Geskus, Martin J Llewelyn, C Louise Thwaites, Sophie Yacoub
BMC Infect Dis
September 3, 2022
DOI: 10.1186/s12879-022-07705-8
Nguyen Van Hao, Huynh Thi Loan, Lam Minh Yen, Evelyne Kestelyn, Duc Du Hong, Duong Bich Thuy, Nguyen Thanh Nguyen, Ha Thi Hai Duong, Tran Thi Diem Thuy, Phung Tran Huy Nhat, Phan Nguyen Quoc Khanh, Nguyen Thi Phuong Dung, Nguyen Hoan Phu, Nguyen Thanh Phong, Pham Thi Lieu, Pham Thi Tuyen, Bui Thi Bich Hanh, Ho Dang Trung Nghia, Pham Kieu Nguyet Oanh, Phan Vinh Tho, Tran Tan Thanh, Hugo C Turner, H Rogier van Doorn, Le Van Tan, Duncan Wyncoll, Nicholas Pj Day, Ronald B Geskus, Guy E Thwaites, Nguyen Van Vinh Chau, C Louise Thwaites
Lancet Glob Health
June 1, 2022
DOI: 10.1016/S2214-109X(22)00117-6
Pisani L, Algera AG, Neto AS, Azevedo L, Pham T, Paulus F, de Abreu MG, Pelosi P, Dondorp AM, Bellani G, Laffey JG, Schultz MJ; ERICC study investigators; LUNG SAFE study investigators; PRoVENT study investigators; PRoVENT-iMiC study investigators
Lancet Glob Health
February 1, 2022
DOI: 10.1016/S2214-109X(21)00485-X
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