Senior Clinical Fellow, Emerging Infections

Associate Professor C. Louise Thwaites

Senior Clinical Research Fellow

Louise Thwaites’ research interests are centred on the care of critically ill patients in resource-restricted settings, including introducing new technologies to address these challenges.

Louise Thwaites is a clinical researcher and member of the Emerging Infections group at OUCRU. She is an Associate Professor in the Centre for Tropical Medicine and Global Health at the University of Oxford.

She is an expert consultant to the World Health Organization and a member of the sepsis in resource-limited settings–expert consensus recommendations group of the European Society of Intensive Care Medicine and CRITICal CARE Asia (Collaboration for Research, Implementation & Training in Intensive CARE in Asia). Louise is a member of the steering committee of the Asia Pacific Sepsis Association and leads the guidelines, policy and quality working group.

She has spent much of her career engaged in research into tetanus. This includes conducting a large randomized controlled trial of magnesium sulphate in tetanus, investigation into the underlying pathophysiology and long-term outcome following tetanus and, more recently, trying to understand which populations are most at risk of tetanus and ways to improve vaccination uptake in these communities.

Her broader research interests also include the management of sepsis and septic shock in resource-limited settings and understanding and preventing hospital-acquired infection in the intensive care unit. She is interested in ways of improving the care of critically ill patients using new technologies.

Her current role in the VITAL project involves developing new devices and technologies for use in diagnosis, treatment and rehabilitation following diseases such as tetanus, sepsis and dengue.

Publications

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Tran Thi Ngoc Dung, Voong Vinh Phat, Chau Vinh, Nguyen Phu Huong Lan, Nguyen Luong Nha Phuong, Le Thi Quynh Ngan, Guy Thwaites, Louise Thwaites, Maia Rabaa, Anh T K Nguyen, Pham Thanh Duy
BMC Infect Dis
March 7, 2024
DOI: 10.1186/s12879-024-09028-2
Nguyen Van Vinh Chau, Tang Chi Thuong, Nguyen Thanh Hung, Nguyen Thi Thu Hong, Du Tuan Quy, Tran Ba Thien, Cao Minh Hiep, Ngo Ngoc Quang Minh, Truong Huu Khanh, Do Duong Kim Han, Truong Hoang Chau Truc, Nguyen Thi Han Ny, Le Kim Thanh, Lam Anh Nguyet, Cao Thu Thuy, Le Nguyen Truc Nhu, Pham Van Quang, Phung Nguyen The Nguyen, Phan Tu Qui, H Rogier van Doorn, C Louise Thwaites, Tran Tan Thanh, Nguyen Thanh Dung, Guy Thwaites, Nguyen To Anh, Le Nguyen Thanh Nhan, Le Van Tan; SEACOVARIANTS1
Emerg Infect Dis
February 1, 2024
DOI: 10.3201/eid3002.231024
RECOVERY Collaborative Group; Peter W Horby, Leon Peto, Natalie Staplin, Mark Campbell, Guilherme Pessoa-Amorim, Marion Mafham, Jonathan R Emberson, Richard Stewart, Benjamin Prudon, Alison Uriel, Christopher A Green, Devesh J Dhasmana, Flora Malein, Jaydip Majumdar, Paul Collini, Jack Shurmer, Bryan Yates, J Kenneth Baillie, Maya H Buch, Jeremy Day, Saul N Faust, Thomas Jaki, Katie Jeffer, Edmund Juszczak, Marian Knight, Wei Shen Lim, Alan Montgomery, Andrew Mumford, Kathryn Rowan, Guy Thwaites, Richard Haynes, Martin J Landray
Nat Commun
January 31, 2024
DOI: 10.1038/s41467-023-43644-x
An Phuoc Luu, Truong Thanh Nguyen, Van Thi Cam Cao, Trinh Hoang Diem Ha, Lien Thi Thu Chung, Trung Ngoc Truong, Tung Nguyen Le Nhu, Khoa Bach Dao, Hao Van Nguyen, Phan Nguyen Quoc Khanh, Khanh Thuy Thuy Le, Luu Hoai Bao Tran, Phung Tran Huy Nhat, Duc Minh Tran, Yen Minh Lam, Catherine Louise Thwaites, Jacob Mcknight, Nguyen Van Vinh Chau, Jennifer Ilo Van Nuil; Vietnam ICU Translational Applications Laboratory (VITAL)
JMIR Res Protoc
January 5, 2024
DOI: 10.2196/44619
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