Evelyne Kestelyn

Evelyne Kestelyn MSc MPH

Head of the Clinical Trials Unit

Evelyne Kestelyn has a Master from the University of Ghent in Comparative Science of Cultures and in Conflict and Development. She went on to pursue a long distance Master in Public Health from the London School of Hygiene and Tropical Medicine after having worked for several years on HIV and RTI’s in Africa. She became involved in Microbicides research and has been a strong advocate for multi purpose prevention technologies to offer women options that protect them against multiple risks; HIV, STIs and/or pregnancy. She is pursuing a PhD on the acceptability and adherence of a contraceptive vaginal ring in Rwanda.

Evelyne is currently acting as Head of the Clinical Trials Unit for the Oxford University Clinical Research Unit in Vietnam. The CTU manages around 64 research projects annually and is working on setting up 12 new clinical trials in the next year. One of her goals is to deliver high quality clinical trial data in a timely and cost-effective manner. She is currently working on the OUCRU Data Sharing policy to push for an institutional sustainable open access policy. Evelyne has a strong interest in Research Ethics, and as a member of the Project for Informed Consent in Africa (PICA) network, she has worked on several informed Consent projects. She is interested in Informed Consent understanding, comprehension and assessments across different countries.

Evelyne has published several articles in international journals.

Key recent research articles:

Adjunctive dexamethasone for the treatment of HIV-uninfected adults with tuberculous meningitis stratified by Leukotriene A4 hydrolase genotype (LAST ACT): Study protocol for a randomised double blind placebo controlled non-inferiority trial. Joseph Donovan, Nguyen Hoan Phu, Le Thi Phuong Thao, …, Ronald B. Geskus, Tran Tinh Hien, Evelyne Kestelyn, Marcel Wolbers, Nguyen Van Vinh Chau, Guy E. Thwaites. Wellcome Open Res 2018, 3:32. dos: 10.12688/wellcomeopenres.14007.1.

Adjunctive dexamethasone for the treatment of HIV-infected adults with tuberculous meningitis (ACT HIV): Study protocol for a randomised controlled trial. Joseph Donovan, Nguyen Hoan Phu, Nguyen Thi Hoang Mai, …, Mugi Nursaya, Kartika Maharani, Tran Tinh Hien, Kevin Baird, Nguyen Huu Lan, Evelyne Kestelyn, Nguyen Van Vinh Chau, Guy E. Thwaites. Wellcome Open Res 2018, 3:31. dos: 10.12688/wellcomeopenres.14006.1

Continuous versus intermittent endotracheal cuff pressure control for the prevention of ventilator-associated respiratory infections in Vietnam: study protocol for a randomised controlled trial. Dat VQ, Geskus RB, Wolbers M, Loan HT, …, Kestelyn E, Wertheim HFL, Wyncoll D, Thwaites GE, van Doorn HR, Thwaites CL, Nadjm B. Trials. 2018 Apr 4;19(1):217. dos: 10.1186/s13063-018-2587-6.

A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults. Mai NT, Dobbs N, Phu NH, Colas RA, Thao LT, Thuong NT, Nghia HD, Hanh NH, Hang NT, Heemskerk AD, Day JN, Ly L, Thu DD, Merson L, Kestelyn E, Wolbers M, Geskus R, Summers D, Chau NV, Dalli J, Thwaites GE. Elife. 2018 Feb 27;7. pii: e33478. dei: 10.7554/eLife.33478.

Clinical features, antimicrobial susceptibility patterns and genomics of bacteria causing neonatal sepsis in a children’s hospital in Vietnam: protocol for a prospective observational study. Toan ND, Darton TC, Boinett CJ, Campbell JI, Karkey A, Kestelyn E, Thinh LQ, Mau NK, Thanh Tam PT, Nhan LNT, Quang Minh NN, Phuong CN, Hung NT, Xuan NM, Thuong TC, Baker S. BMJ Open. 2018 Jan 24;8(1):e019611. doi: 10.1136/bmjopen-2017-019611.

Co-trimoxazole versus azithromycin for the treatment of undifferentiated febrile illness in Nepal: study protocol for a randomized controlled trial. Pokharel S, Basnyat B, Arjyal A, Mahat SP, Kc RK, Bhuju A, Poudyal B, Kestelyn E, Shrestha R, Phuong DNT, Thapa R, Karki M, Dongol S, Karkey A, Wolbers M, Baker S, Thwaites G. Trials. 2017 Oct 2;18(1):450. doi: 10.1186/s13063-017-2199-6.