Dr Le Van Tan, PhD.
Head of Emerging Infections Group
Dr Le Van Tan joined the OUCRU family in 2003. He received a PhD in Life and Biomolecular Sciences from the Open University in the UK in 2011. His early work focused on pathogen discovery, which led the to discovery of a novel cyclovirus in 4% of Vietnamese patients with encephalitis.
Since 2013 he is a member of the Wellcome Trust Fellows. His Training Fellowship (2013 – 2017) aimed to study molecular epidemiology of Hand, Foot and Mouth Disease in Vietnam and its implication for vaccine development and implementation. Currently, he holds a Wellcome Trust Intermediate Fellowship (2017 – 2022) to study the translational potential of new technologies such as mass spectrometry and next-generation sequencing in patients with brain infections in Vietnam, and an NIH funding support to explore novel cause(s) of sepsis in Southeast Asia.
As an independent investigator, his aim is to develop local and national expertise within Vietnam and the wider region so that ongoing and future emerging infectious disease challenges can be addressed from within the affected regions and communities.
Key publications/journal articles:
N.T.H. Mai, N.H. Phu, L.N.T. Nhu, N.T.T. Hong, N.H.H. Hanh, L.A. Nguyet, T.M. Phuong, A. McBride, D.Q. Ha, H.D.T. Nghia, N.V.V. Chau, G. Thwaites and L.V. Tan, Central nervous system infection diagnosis by next generation sequencing: a glimpse into the future? Open Forum Infectious Diseases, 2017 (DOI: 10.1093/ofid/ofx046)
A. McBride, T.T.H. Chau, N.T.T Hong, N.T.H Mai, N.T. Anh, T.T Thanh, T.T. Van, L.T. Xuan, T.P.M. Sieu, L.H Thai, L.V. Chuong, D.X. Sinh, N.D. Phong, N.H. Phu, J. Day, H.D.T Nghia, T.T. Hien, N.V.V Chau, G. Thwaites, L.V. Tan, Angiostrongylus cantonensis is an Important Cause of Eosinophilic Meningitis in Southern Vietnam., Clinical Infectious Diseases, 2017, PMID 28158507
J. L. Geoghegan*, L.V. Tan *, D. Kuhnert, D. Wentworth, R. Halpin, N.M. Ngoc, L.T.T. Uyen, N.T.K. Tuyen, T.T. Thanh, V.T.T Hang, P.T. Qui, N.T. Hung, T.H. Khanh, L.Q. Thinh, L.N.T Nhan, H.M.T. Van, D.C. Viet, H.M. Tuan, H.L Viet, T.T. Hien, N.V.V. Chau, G. Thwaites, Tanja Stadler, E.C. Holmes, H.R. van Doorn, Phylodynamics of Enterovirus A71-Associated Hand, Foot and Mouth Disease in Viet Nam(Journal of Virology. 2015 Jun 17. pii: JVI.00706-15.) *Contributed equally to this work and corresponding authors. PMID: 26085170
L.V. Tan, L.H. Thai, N.H. Phu, H.D.T. Nghia, L.V. Chuong, D.X. Sinh, N.D. Phong, N.T.H. Mai, D.N.H. Man, V.M. Hien, N.T. Vinh, J. Day, N.V.V Chau, T.T. Hien, J. Farrar, M.D. de Jong, G. Thwaites, H.R. van Doorn, T.T.H. Chau, Viral aetiology of central nervous system infections in adults admitted to a tertiary referral hospital in southern Vietnam over 12 years. PLoS Neglected Tropical Diseases, 2014. 8(8): p. e3127. PMID: 25165820
L.V. Tan, H.R. van Doorn, H.D.T. Nghia, T.T.H. Chau, L.T.P. Tu, M. de Vries, M. Canuti, M. Deijs, M. F Jebbink, S. Baker, J.E. Bryant, N.T. Tham, N.T.T. Chinh BKrong, M.F. Boni, T.Q. Loi, J.T.P. Verhoeven, M. Crusat, R.E. Jeeninga, C. Schultsz, N.V.V Chau, T.T. Hien, L. van der Hoek, J. Farrar, M.D. de Jong, Identification of a new cyclovirus in cerebrospinal fluid of patients with acute central nervous system infections. MBio, 2013; 4(3), PMID: 23781068